Chris Twelves : rechercher sur Z-Library

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1

Change in topoisomerase 1 (Top1) positive circulating tumor cells impacts overall survival in patients with advanced breast cancer after treatment with etirinotecan pegol

Rugo, Hope S., Cortes, Javier, Awada, Ahmad, O'Shaughnessey, Joyce, Twelves, Chris J, Im, Seock-Ah, Hannah, Alison, Lu, Lin, Sy, Sherwin, Caygill, Katie, Zajchowski, Deborah A, Davis, Darren W., Tagli

Journal:

Clinical Cancer Research

Année:

2018

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2018

2

A phase 1b/2, open-label, dose-escalation, and dose-confirmation study of eribulin mesilate in combination with capecitabine

Twelves, Chris, Anthoney, Alan, Savulsky, Claudio I., Guo, Matthew, Reyderman, Larisa, Cresti, Nicola, Semiglazov, Vladimir, Timcheva, Constanta, Zubairi, Ishtiaq, Morrison, Rosemary, Plummer, Ruth, E

Journal:

British Journal of Cancer

Année:

2019

Langue:

english

Fichier:

PDF, 510 KB

english, 2019

3

CApecitabine plus Radium-223 (Xofigo™) in breast cancer patients with BONe metastases (CARBON): study protocol for a phase IB/IIA randomised controlled trial

Coleman, Rob, Brown, Janet, Rathbone, Emma, Flanagan, Louise, Reid, Amber, Kendall, Jessica, Howell, Sacha, Twelves, Chris, Palmieri, Carlo, Anand, Anjana, MacPherson, Iain, Brown, Sarah

Journal:

Année:

2020

Langue:

english

Fichier:

PDF, 1.42 MB

english, 2020

4

Systemic treatment of hormone receptor positive, human epidermal growth factor 2 negative metastatic breast cancer: retrospective analysis from Leeds Cancer Centre

Twelves, Chris, Cheeseman, Sue, Sopwith, Will, Thompson, Matthew, Riaz, Majid, Ahat-Donker, Necibe, Myland, Melissa, Lee, Adam, Przybysz, Raymond, Turner, Stuart, Hall, Geoff, Perren, Tim

Journal:

Année:

2020

Langue:

english

Fichier:

PDF, 1.39 MB

english, 2020

5

Repurposing anticancer drugs for COVID-19-induced inflammation, immune dysfunction, and coagulopathy

Saini, Kamal S., Lanza, Carlo, Romano, Marco, de Azambuja, Evandro, Cortes, Javier, de las Heras, BegoÃ±a, de Castro, Javier, Lamba Saini, Monika, Loibl, Sibylle, Curigliano, Giuseppe, Twelves, Chris,

Journal:

British Journal of Cancer

Année:

2020

Fichier:

PDF, 284 KB

2020

6

Capecitabine plus docetaxel combination therapy : Cost-effectiveness in patients with anthracycline-pretreated advanced breast carcinoma

Shailendra Verma, Dominique Maraninchi, Joyce O'Shaughnessy, Carol Jamieson, Stephen Jones, Miguel Martín, Joseph McKendrick, David Miles, Chris Twelves, John Hornberger

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 120 KB

english, 2005

7

Effect of renal impairment on the pharmacokinetics and tolerability of capecitabine (Xeloda) in cancer patients

Christopher Poole, Jill Gardiner, Chris Twelves, Patrick Johnston, Peter Harper, Jim Cassidy, Jayne Monkhouse, Ludger Banken, Erhard Weidekamm, Bruno Reigner

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2002

Langue:

english

Fichier:

PDF, 128 KB

english, 2002

8

A population model of epirubicin pharmacokinetics and application to dosage guidelines

Lorraine D. Ralph, Alison H. Thomson, Nicola A. Dobbs, Chris Twelves

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 313 KB

english, 2003

9

A phase I study of ZD0473 combined with paclitaxel for the treatment of solid malignancies

Chris Twelves, Martin Reck, Alan Anthoney, Ulrich Gatzemeier, Stan Kaye

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 171 KB

english, 2003

10

The effect of different etiologies of hepatic impairment on the pharmacokinetics of gefitinib

Jiri Horak, Jeff White, Adrian L. Harris, Mark Verrill, James Carmichael, Alison Holt, Mireille Cantarini, Merran Macpherson, Alan Swaisland, Helen Swaisland, Chris Twelves

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 331 KB

english, 2011

11

Bioequivalence of two tablet formulations of capecitabine and exploration of age, gender, body surface area, and creatinine clearance as factors influencing systemic exposure in cancer patients

Jim Cassidy, Chris Twelves, David Cameron, William Steward, Ken O'Byrne, Duncan Jodrell, Ludger Banken, Timothy Goggin, David Jones, Brigitte Roos, Erine Bush, Erhard Weidekamm, Bruno Reigner

Journal:

Cancer Chemotherapy and Pharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 185 KB

english, 1999

12

Bioavailability study of oral and intravenous OGT 719, a novel nucleoside analogue with preferential activity in the liver

Ricky A. Sharma, Martin M. Eatock, Christopher J. Twelves, Gill Brown, Heather R. McLelland, Kathryn T. Clayton, Kenneth J. O'Byrne, Chris Moyses, James Carmichael, William P. Steward

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2001

Langue:

english

Fichier:

PDF, 92 KB

english, 2001

13

Maximum a posteriori Bayesian estimation of epirubicin clearance by limited sampling

Lorraine D. Ralph, Alison H. Thomson, Nicola A. Dobbs, Chris Twelves

Journal:

British Journal of Clinical Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 168 KB

english, 2004

14

Assessment of the validity of a population pharmacokinetic model for epirubicin

Lorraine D. Ralph, Marie Sandstrom, Chris Twelves, Nicola A. Dobbs, Alison H. Thomson

Journal:

British Journal of Clinical Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 180 KB

english, 2006

15

Activity of Doxorubicin Covalently Bound to a Novel Human Serum Albumin Microcapsule

Martin Eatock, Nicola Church, Roy Harris, Wilson Angerson, Colin McArdle, Ray French, Chris Twelves

Journal:

Investigational New Drugs

Année:

1999

Langue:

english

Fichier:

PDF, 137 KB

english, 1999

16

In situ detection of HER2:HER2 and HER2:HER3 protein–protein interactions demonstrates prognostic significance in early breast cancer

Melanie Spears, Karen J. Taylor, Alison F. Munro, Carrie A. Cunningham, Elizabeth A. Mallon, Chris J. Twelves, David A. Cameron, Jeremy Thomas, John M. S. Bartlett

Journal:

Breast Cancer Research and Treatment

Année:

2012

Langue:

english

Fichier:

PDF, 401 KB

english, 2012

17

Clinical response to eribulin in patients with metastatic breast cancer is independent of time to first metastatic event. EMBRACE study group

Javier Cortes, Chris Twelves, Jantien Wanders, Wenquan Wang, Linda Vahdat, Corina Dutcus

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 56 KB

english, 2011

18

Optimizing the management of HER2-negative metastatic breast cancer with capecitabine (Xeloda)

Robert Leonard, David Miles, Peter Reichardt, Chris Twelves

Journal:

Seminars in Oncology

Année:

2004

Langue:

english

Fichier:

PDF, 159 KB

english, 2004

19

Quality of Life in Women with Advanced Breast Cancer Treated with Docetaxel

Chris J. Twelves, David W. Miles, Angela Hall

Journal:

Clinical Breast Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 118 KB

english, 2004

20

Phase III Trials of Eribulin Mesylate (E7389) in Extensively Pretreated Patients With Locally Recurrent or Metastatic Breast Cancer

Chris Twelves, Javier Cortes, Linda T. Vahdat, Jantien Wanders, Corina Akerele, Peter A. Kaufman

Journal:

Clinical Breast Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 200 KB

english, 2010

21

Phase I study and pharmacokinetic of CHS-828, a guanidino-containing compound, administered orally as a single dose every 3 weeks in solid tumours: An ECSG/EORTC study

Alain Ravaud, Thomas Cerny, Catherine Terret, Jantien Wanders, Binh Nguyen Bui, Dagmar Hess, Jean-Pierre Droz, Pierre Fumoleau, Chris Twelves

Journal:

European Journal of Cancer

Année:

2005

Langue:

english

Fichier:

PDF, 108 KB

english, 2005

22

Erlotinib in combination with capecitabine and docetaxel in patients with metastatic breast cancer: A dose-escalation study

Chris Twelves, José M. Trigo, Rob Jones, Flavio De Rosa, Ashok Rakhit, Scott Fettner, Tonya Wright, José Baselga

Journal:

European Journal of Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 190 KB

english, 2008

23

Loading doses for costly cancer biologicals: A cause for concern or tilting at windmills?

Ivo M. Hennig, Chris Twelves

Journal:

European Journal of Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 131 KB

english, 2008

24

New prognostic factors and calculators for outcome prediction in patients with recurrent glioblastoma: A pooled analysis of EORTC Brain Tumour Group phase I and II clinical trials

Thierry Gorlia, Roger Stupp, Alba A. Brandes, Roy R. Rampling, Pierre Fumoleau, Christian Dittrich, Mario M. Campone, Chris C. Twelves, Eric Raymond, Monika E. Hegi, Denis Lacombe, Martin J. van den B

Journal:

European Journal of Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 216 KB

english, 2012

25

Older people with cancer: perceptions and feelings about information, decision-making and treatment—a pilot study

Zoe Chouliara, Morven Miller, David Stott, Alexander Molassiotis, Chris Twelves, Nora Kearney

Journal:

European Journal of Oncology Nursing

Année:

2004

Langue:

english

Fichier:

PDF, 282 KB

english, 2004

26

Sequential docetaxel as adjuvant chemotherapy for early breast cancer (TACT): an open-label, phase III, randomised controlled trial

Paul Ellis, Peter Barrett-Lee, Lindsay Johnson, David Cameron, Andrew Wardley, Susan O'Reilly, Mark Verrill, Ian Smith, John Yarnold, Robert Coleman, Helena Earl, Peter Canney, Chris Twelves, Christop

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 290 KB

english, 2009

27

Capecitabine monotherapy in metastatic colorectal cancer

Chris Twelves, Danielle Hargreaves, Jonathan Nguyen-Van-Tam, Thomas Ng

Journal:

The Lancet Oncology

Année:

2001

Langue:

english

Fichier:

PDF, 82 KB

english, 2001

28

Predictive markers of anthracycline benefit: a prospectively planned analysis of the UK National Epirubicin Adjuvant Trial (NEAT/BR9601)

John MS Bartlett, Alison F Munro, Janet A Dunn, Christopher McConkey, Sarah Jordan, Chris J Twelves, David A Cameron, Jeremy Thomas, Fiona M Campbell, Daniel W Rea, Elena Provenzano, Carlos Caldas, Pa

Journal:

The Lancet Oncology

Année:

2010

Langue:

english

Fichier:

PDF, 134 KB

english, 2010

29

Capecitabine (Xeloda®): From the Laboratory to the Patient's Home

George Pentheroudakis, Chris Twelves

Journal:

Clinical Colorectal Cancer

Année:

2002

Langue:

english

Fichier:

PDF, 133 KB

english, 2002

30

Capecitabine/Oxaliplatin, a Safe and Active First-Line Regimen for Older Patients Metastatic Colorectal Cancer: Post Hoc Analysis of a Large Phase II Study

Chris J. Twelves, Charles A. Butts, Jim Cassidy, Thierry Conroy, Filippo de Braud, Eduardo Díaz-Rubio, Josep M. Tabernero, Patrick Schöffski, Arie Figer, René Brunet, Johannes Grossmann, Alberto F. So

Journal:

Clinical Colorectal Cancer

Année:

2005

Langue:

english

Fichier:

PDF, 887 KB

english, 2005

31

Xeloda® in Adjuvant Colon Cancer Therapy (X-ACT) Trial: Overview of Efficacy, Safety, and Cost-Effectiveness

Chris J. Twelves

Journal:

Clinical Colorectal Cancer

Année:

2006

Langue:

english

Fichier:

PDF, 180 KB

english, 2006

32

Population pharmacokinetic-pharmacodynamic modelling and simulation of neutropenia induced by TP300, a novel topoisomerase I inhibitor

Saito, Tomohisa, Iida, Satofumi, Abe, Masaichi, Jones, Keith, Kawanishi, Takehiko, Twelves, Chris

Journal:

Journal of Pharmacy and Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2013

33

Tubulin: an example of targeted chemotherapy

Seligmann, Jenny, Twelves, Chris

Journal:

Future Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 866 KB

english, 2013

34

Cost-Effective Strategies in the Management of Advanced Colorectal Cancer

Lucy C. Scott, Dr Chris Twelves

Journal:

American Journal of Cancer

Année:

2003

Langue:

english

Fichier:

PDF, 149 KB

english, 2003

35

Capecitabine as Adjuvant Treatment for Stage III Colon Cancer

Twelves, Chris, Wong, Alfred, Nowacki, Marek P., Abt, Markus, Burris, Howard, Carrato, Alfredo, Cassidy, Jim, Cervantes, Andrés, Fagerberg, Jan, Georgoulias, Vassilis, Husseini, Fares, Jodrell, Duncan

Journal:

Boston Medical and Surgical Journal

Année:

2005

Langue:

english

Fichier:

PDF, 124 KB

english, 2005

36

Long-term clinical effect and safety of sebelipase alfa in adults with lysosomal acid lipase deficiency

Whitley, Chester B., Valayannopoulos, Vassili, Malinová, Věra, Sharma, Reena, Bourdon, Chris, Boyadjiev, Simeon A., Kessler, Bruce, Twelves, Christopher, Tripuraneni, Radhika, Eckert, Stephen, Schneid

Journal:

Molecular Genetics and Metabolism

Année:

2014

Langue:

english

Fichier:

PDF, 68 KB

english, 2014

37

Sunbed use in children aged 11-17 in England: face to face quota sampling surveys in the National Prevalence Study and Six Cities Study

Catherine S Thomson, Sarah Woolnough, Matthew Wickenden, Sara Hiom and Chris Twelves

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 293 KB

english, 2010

38

Trials and tribulations of cytotoxic and targeted breast cancer therapy: a clinical perspective on the next phase of progress

Journal:

Expert Review of Anticancer Therapy

Année:

2013

Langue:

english

Fichier:

PDF, 707 KB

english, 2013

39

DNA: Still A Target Worth Aiming At?

Dr D. Alan Anthoney,Chris J. Twelves

Journal:

American Journal of PharmacoGenomics

Année:

2001

Langue:

english

Fichier:

PDF, 275 KB

english, 2001

40

Effect of adjuvant capecitabine or fluorouracil, with or without oxaliplatin, on survival outcomes in stage III colon cancer and the effect of oxaliplatin on post-relapse survival: a pooled analysis of individual patient data from four randomised controlled trials

Schmoll, Hans-Joachim, Twelves, Chris, Sun, Weijing, O'Connell, Michael J, Cartwright, Thomas, McKenna, Edward, Saif, Muhammad, Lee, Steve, Yothers, Greg, Haller, Daniel

Journal:

The Lancet Oncology

Année:

2014

Langue:

english

Fichier:

PDF, 440 KB

english, 2014

41

Oral uracil-tegafur: an alternative to intravenous 5-fluorouracil?

Twelves, Chris, Jones, Rob

Journal:

Expert Opinion on Pharmacotherapy

Année:

2001

Langue:

english

Fichier:

PDF, 163 KB

english, 2001

42

Erratum to: Efficacy of eribulin in women with metastatic breast cancer: a pooled analysis of two phase 3 studies

Twelves, Chris, Cortes, Javier, Vahdat, Linda, Olivo, Martin, He, Yi, Kaufman, Peter A., Awada, Ahmad

Journal:

Breast Cancer Research and Treatment

Année:

2015

Langue:

english

Fichier:

PDF, 119 KB

english, 2015

43

Effect of erlotinib on CYP3A activity, evaluated in vitro and by dual probes in patients with cancer

Calvert, Hilary, Twelves, Chris, Ranson, Malcolm, Plummer, Ruth, Fettner, Scott, Pantze, Michael, Ling, Jie, Hamilton, Marta, Lum, Bert L., Rakhit, Ashok

Journal:

Anti-Cancer Drugs

Année:

2014

Langue:

english

Fichier:

PDF, 561 KB

english, 2014

44

Efficacy of eribulin in women with metastatic breast cancer: a pooled analysis of two phase 3 studies

Twelves, Chris, Cortes, Javier, Vahdat, Linda, Olivo, Martin, He, Yi, Kaufman, Peter A., Awada, Ahmad

Journal:

Breast Cancer Research and Treatment

Année:

2014

Langue:

english

Fichier:

PDF, 321 KB

english, 2014

45

Effect of sebelipase alfa after 2years in adults with lysosomal acid lipase deficiency

Rojas-Caro, Sandra, Whitley, Chester, Valayannopoulos, Vassili, Malinová, Věra, Sharma, Reena, Bourdon, Chris, Boyd, Simeon, Kessler, Bruce, Twelves, Christopher, Eckert, Stephen, Quinn, Anthony G.

Journal:

Molecular Genetics and Metabolism

Année:

2015

Langue:

english

Fichier:

PDF, 175 KB

english, 2015

46

Is oxaliplatin combined with weekly bolus 5-fluorouracil and leucovorin an option for stage II and III colon cancer?

Journal:

Nature Clinical Practice Oncology

Année:

2008

Langue:

english

Fichier:

PDF, 129 KB

english, 2008

47

Breast cancer-related lymphoedema and venepuncture: a review and evidence-based recommendations

Jakes, Adam D., Twelves, Chris

Journal:

Breast Cancer Research and Treatment

Année:

2015

Langue:

english

Fichier:

PDF, 642 KB

english, 2015

48

Etirinotecan pegol (NKTR-102) versus treatment of physician's choice in women with advanced breast cancer previously treated with an anthracycline, a taxane, and capecitabine (BEACON): a randomised, open-label, multicentre, phase 3 trial

Perez, Edith A, Awada, Ahmad, O'Shaughnessy, Joyce, Rugo, Hope S, Twelves, Chris, Im, Seock-Ah, Gómez-Pardo, Patricia, Schwartzberg, Lee S, Diéras, Veronique, Yardley, Denise A, Potter, David A, Maill

Journal:

The Lancet Oncology

Année:

2015

Langue:

english

Fichier:

PDF, 480 KB

english, 2015

49

‘Tablet burden’ in patients with metastatic breast cancer

Milic, Marina, Foster, Anna, Rihawi, Karim, Anthoney, Alan, Twelves, Chris

Journal:

European Journal of Cancer

Année:

2016

Langue:

english

Fichier:

PDF, 693 KB

english, 2016

50

Cytotoxic chemotherapy: Still the mainstay of clinical practice for all subtypes metastatic breast cancer

Twelves, Chris, Jove, Maria, Gombos, Andrea, Awada, Ahmad

Journal:

Critical Reviews in Oncology/Hematology

Année:

2016

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2016